2021 Ford E-350 owner complaints
22 complaints filed with NHTSA, including 1 crash, 0 fires, 0 injuries and 0 deaths.
Problems by component
Service Brakes, Hydraulic5 Forward Collision Avoidance1 Recent complaints
September 13, 2026Engine
Engine failure on a 2021 Ford E-350 cutaway, 7.3L V8, used for parcel delivery. The vehicle was taken out of service and has not run since. Two diagnoses, both in writing. ACME Mobile Service, July 27, 2026, at 152,760 miles: "Found the #5 cylinder is completely disabled and dropped out. Truck will need a new motor." Ford of Spartanburg (Ford dealership), Repair Order 595835, August 25, 2026: "FOUND ENGINE IS KNOCKING, WILL NEED TO REPLACE MOTOR." Ford quoted $16,000.82 for a long-block replacement. The engine is available for inspection. This is the second engine failure on this VIN. In March 2023 at 83,575 miles the engine was rebuilt with new Ford parts (camshaft, sixteen lifters, rocker
September 13, 2026Engine
Engine misfire on a 2021 Ford E-350 cutaway, 7.3L V8, used for parcel delivery. The vehicle was delivered to Ford of Spartanburg (Ford dealership) for diagnosis. The vehicle is still out of service. Ford's diagnosis, Repair Order 593079, June 26, 2026: "WILL NEED TO REPLACE ALL SPARK PLUGS AND WIRES, WILL ALSO NEED TO REPLACED ALL COILS DUE TO MISFIRES ON ALMOST EVERY CYLINDER." The Ford service advisor wrote the same day: "The engine also has a misfire that is unrelated to the transmission concern." Ford quoted $4,376.35 for the ignition components and wrote: "AFTER REPAIRING TRANSMISSION WILL NEED TO DIAGNOSE ALL OTHER CONCERNS WITH VEHICLE, CANNOT DIAG ANYTHING AT MOMENT DUE TO NOT BEING
January 31, 2026Engine
fatal Camshaft and lifter failure requiring an engine replacement
November 28, 2025Engine
Engine failure at 78,172, excess wear to the camshaft lobes and valve tappet surface. We have had 22 failures. There was a recall -24B27 for 2021 and 2022 models year for idle oil pressure. Most vans had 70 to 80k on them by the time we received a letter. Some engine have been changed twice. Ford has a serious problem and is not acknowledging it. Please help! Montachusett Regional Transit Authority , Fitchburg MA 01420
February 17, 2025Engine
This is one of 4 of my 2021 ford econoline fleet vehicles purchased in 2021 that have had engine failure. I am one of many contractors in my area and others around the country who have had this issue with the same F59 engine. Ford has failed to issue a recall.